IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release.

编号: 144785
中文名称: Anti-Infective Peptide s
英文名: Anti-Infective Peptide s
英文同义词: SB-75 diacetate
CAS号: 940291-10-1
单字母: H2N-KSRIVPAIPVSLL-CONH2
三字母: H2N-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-CONH2
氨基酸个数: 13
分子式: C65H118N18O15
平均分子量: 1391.74
精确分子量: 1390.9
等电点(PI): -
pH=7.0时的净电荷数: 2.97
平均亲水性: -0.37272727272727
疏水性值: 1.05
外观与性状: 白色粉末状固体

参考文献：
Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72. : https://pubmed.ncbi.nlm.nih.gov/17384586
Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23. : https://pubmed.ncbi.nlm.nih.gov/24021961