Endothelin 1 (swine, human) 

同义词：内皮缩血管肽 1 (猪,人)

分子量：2491.90
分子式：C109H159N25O32S5
CAS 号：117399-94-7
三字母：Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)

单字母：CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)    

产品描述：

Endothelin 1 (swine, human) 是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体ETA和ETB发挥作用。

体外研究：

Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a vasoconstrictive action, ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species. It is claimed that ET-1 induces proinflammatory mechanisms, increasing superoxide anion production and cytokine secretion。